Cyclica Inc. Product Team
Users can now predict ADMET properties of molecules through its novel POEM algorithm through the LigandExpress platform
Property Prediction supports the submission of small chemical libraries
ADMET models are available and ready to use without time-consuming hyper parameterization
Results are generated quickly through Cyclica’s high performance computing infrastructure
The entire Ligand Express platform has been migrated to Python 3, and many software dependencies have been updated
Improved handling of UTF-8 text data throughout the site and database
Future-proof to survive the Python 2 End-of-Life date on Jan 1, 2020
Sets the stage for future enhancements by empowering our developers with new Python 3.x-exclusive features
Improves security by staying up to date on any security-related patches
Added loading spinner to the Variant Table body
Fixed an error that occurred when applying a filter that returned less pages than the page you currently were on
Fixed an issue on Chrome that caused filters to fail when applying the “OR” operator
Improved messaging decoupling the rank (assigned through the MatchMaker engine) from the binding pose (generated through conventional docking)
Copy SMILES on “Run Summary” module functionality restored
Rank is now correctly displayed as Rank Percentile. Score has been removed.
Fixed Abstract retrieval for the Disease Network Graph which previously broke when more than one article was returned.
Removed the display of “New Project” button for users with “Team Member” status.
Removed residual display of ligand heteroatoms when the protein is represented by “ball-and-stick” and the ligand visualization is “off”
Fixed “Protein Viewer” display issues when no docked structure is available and the Variant Table is expanded
Pinning proteins on graphs: Functionality has been temporarily removed