A New Filter and Improved UX for Property Prediction
With a focus on building the infrastructure for some upcoming features, this month’s Release highlights reports on small, but pivotal changes to the platform. We have integrated subcellular location as a filter, allowing users to refine the putative binding list to proteins that are expressed in relevant cellular compartments. Another initiative saw improvements to the interface of Property Prediction. Users can now select top molecules from within a library, and add it to another library on the fly, allowing for easy small molecule comparisons.
Scroll down to view the new location filter in action and how to add compounds to other libraries from within the library view.
Proteome screening examines over 8000 human proteins, finding all proteins that are likely to interact with a query molecule. Top ranking protein-ligand interactions can be further refined by filtering results with the many available systems biology filters embedded within Ligand Express, including diseases, gene ontology, and more. The “Location” filter allows users to search the available subcellular compartments, and isolate for proteins expressed within these compartments.
Populate a Library from an Existing Library
Compounds with results from Property Prediction can be readily compared to one another. In some cases, a researcher may want to compare the top compounds from several libraries to one another. To facilitate the creation of “best-of” libraries, it is now possible to add compounds from within the library view to another library. Simply sort compounds within a library to identify top molecules, select their checkboxes, and move the compounds to a new library.
This month will continue to focus on refining the user experience delivered by Property Prediction, with preparations being made to allow users to upload their own data. Also, expect additional changes to Proteome Screening as we prepare for some new features to be implemented in the upcoming months. Follow our Linkedin page here and our Twitter page here for updates as the become available.
For all updates from this month’s release and more, please visit https://cyclicarx.com/product.
Are you a fan of the changes made to Ligand Express? All feedback is greatly appreciated! We would love to hear from you, please send any feedback to firstname.lastname@example.org.